Good morning. Daphne Koller is one of the leaders you want to know what is possible. The pioneer of machine learning, Professor Stanford and Partner MacArthurshe became the co-founder and co-CEO of Coursera. Now Kohler spends most of her time in a lifelong passion as CEO and founder that blends biology and machine learning passion for life inherenta drug discovery and development company.
She believes that just as calculus has revolutionized our understanding of physics by providing a mathematical framework to make predictions, AI can now do the same for the “complex and intertwined” field of biology. In the next episode of Leadership this week, Koller explains that her company has become the cusp of potentially transformative new therapies for fatty liver disease and ALS.
She talks about this new era of personalization and has made unimaginable progress in drug discovery. But she also talked about how she was awarded a MacArthur “Genius” grant in 2004, which proved to be a catalyst for expanding into the entrepreneurial world.
“I’ve always had a very aspiring definition of what genius means. That’s Albert Einstein or Leonardo and Wenqi. She said, this is not me. I feel very humble and unworthy, and some even say that after the MacArthur Award, most of my career journey has been trying to repay it and prove that I deserve it. ”
“My parents were scholars. I firmly believe I would retire, become an academic, and become an emeritus professor like my father.” MacArthur Grant gave her the freedom to think more broadly about how she could make an impact: “I want to do something that directly changes the world, not publish papers and hope someone will read these papers and do something about it.”
That period planted the seeds of an idea that would become her company that began with Andrew Ng. “I was absolutely frightened. Not only did I never set up a company, but my career journey kept me from even a never even Arrived In a company,” she added.
But today, she embraces both the power of scientists and CEOs. “I don’t know what a genius is, but I can tell you that one thing I think is my superpower, trying to avoid female impostor syndrome is the ability to connect points in different disciplines and connect clearly in review, but it wasn’t obvious at the time.”
Contact CEO every day through Diane Brady diane.brady@fortune.com
Top news
Apple COO retires, after changes to Tim Cook succession pictures
Apple’s Jeff Williams will retire after 27 years at the company. He is the “most likely” contender to replace 64-year-old Tim Cook as CEO According to New York. The new COO will be Sabih Khan, who has worked with the company for 30 years. If the chef takes a step back, he may be a competitor in the CEO role, including hardware engineering head John Ternus; software director Craig Federighi; and service director Eddy Cue.
Trump causes turmoil in copper market
Copper prices hit record after President Trump Say he will impose Importing widely used metals is subject to a 50% tariff. The president of the Canadian Mining Association warned that the United States has no production capacity to meet its needs and therefore it will raise its own prices. JPMorgan analysts estimate that ratio is only 25%. Copper price Falled In the non-U.S. market, buyers expect demand from U.S. customers to decrease. In other places: WSJ has A great long reading On how Trump decided to postpone the tariff deadline until August 1.
Investors are bored with tariff dance
UBS strategist Nadia Lovell explain Investors were willing to “browse” President Trump’s tariff threat as a negotiation strategy on Tuesday, which is why the market reacted to the president’s doubling of import restrictions this week. However, Lovell believes that “at some point, rubber has to be on the road.”
Trump attacks Powell, again
President Trump once again urged U.S. Federal Reserve Chairman Jerome Powell to resign if he misleads testimony about the refurbishment of the Fed’s headquarters. President – Positive critic of Powell’s interest rate policy –No evidence was provided What did Powell say wrong.
Trump administration on the board of climate change skeptics
Three scientists who doubt global warming Hired now New York-era New York State reported that at the Department of Energy, Trump fired hundreds of researchers monitoring how climate change affects the United States
Musk tells Ives to put the socks inside
Elon Musk told Daniel Ives that he has long been bullish on Tesla stock.shut up” In a post on X yesterday. Ives proposed Tesla’s board of directors intervened to limit Musk’s political activities, which Ives believes has dispersed Musk’s main mission at Tesla, thus damaging the stock.
Groke praised Hitler
Elon Musk’s AI Chatbot Grok when asked to comment on controversial social media posts referring to children who died in a recent Texas summer camp flood Praise Hitler. “There is no doubt about dealing with this mean anti-white hatred? Adolf Hitler. “If calling on radicals to cheer dead children will make me ‘literally Hitler’, then go through the beard – the truth is more than just a flood. ” AI researchers have Musk accused Give him the AI right-wing bias.
Flood death toll rises
161 people are still missing after flash floods in Kerr County, with deaths rising by at least 109 Texas officials say. 444 people have been found alive.
Golden Day strategy
Amazon’s four-day Golden Day event kicked off yesterday, delaying the e-commerce industry as trade uncertainty and the use of generating AI in bargaining. Seller on the website describe arrive wealth They plan how to balance the influx of shoppers with tariff concerns.
Fortune 500 Powerful Mobile
Baxter International (No. 288) appointment Andrew hid As CEO, work on September 3, 2025 no later than 2025 Brent shaverappointed to the position after the former CEO José Almeida retire.
Hershey (No. 379) appointment Kirk cobbler As CEO, effective August 18. Tanner previously served as CEO of Wendy’s and will succeed Michelle Barkershe announced her retirement in January.
Every Friday morning, the weekly Fortune 500 Powermoves Column Track 500 Fortune 500 Company C-Suite Shifts Shifts–View the latest version.
market
- S&P 500 Futures Yesterday the index itself closed at 6,225 yesterday and was flat in listing trading this morning. Asian market Except for China, most of this morning CSI 300 Sink 0.18%, Hang Forest Lost a little in Hong Kong. Stoxx Europe 600 Early trading grew by 0.5%. UK FTSE 100 As it finally got higher, it rose by 0.22%. Bitcoin Still below $108K.
From the analyst
- Tesla’s weddingbush: “Tesla’s board of directors must take action and set basic rules for Musk; the soap opera must end: After leaving the Trump administration a few months ago and making elements, Musk has now formally formed a new party called the “American Party.” The party will conduct core research independently, while discussions on legislation will be with Musk’s Musk, which we think is a committee. Musk is centered around his political ambitions and actions.”
- Pantheon Macroeconomics on OBBBA: “Many businesses will welcome the signing of a large billing law to reduce uncertainty and encourage investment and to encourage investment through some new tax breaks. However, tariffs are making imported capital goods more expensive, and their outlook remains very uncertain, and yesterday’s letters were less willing to perform from trading partners. Samuel’s Grave and Olver Allen’s following year stagnation.
- Apollo’s disruption between bond and stock markets: “The bond market continues to cut for the next Fed’s action, expecting growth to slow down. However, the stock market is trading higher relative to its defensive capabilities, expecting growth to accelerate… The bond market is inconsistent. The bond market is wrong and the growth rate due to accelerated growth is reduced, or the growth rate of stocks is reduced.
Around the water cooler
Elon Musk Chris Morris
User accuses Elon Musk of Gluck (Xai) of changing its internal descriptions, tilting to the right to assume that the media’s viewpoint is “biased” By Marco Quiroz-Gutierrez
CEO Daily is edited and edited by Joey Abrams and Jim Edwards.
